Alpha GPC (Choline Alfoscerate, CAS No.28319-77-9) BENEFITS & INFORMATION

Alpha GPC (Choline Alfoscerate, CAS No.28319-77-9)

Other name : Alpha GPC, Choline Alfoscerate, Choline alphoscerate, Choline glycerophosphate, 

Glycerophosphorylcholine, Alfa-GPC, Alpha Glycerol Phosphoryl Choline, Alpha-Glyceryl Phosphoryl Choline, Alpha-Glyceryl Phosphatidylcholine, Alpha-Glycerylphosphorylcholine, GPC, GroPCho, L-A-Glyceryl Phosphorylcholine, L-alpha-glycerylphosphorylcholine.

Appearance:

50%, 99% white powder

85% Transparent liquid

Basic information: 

CAS No.28319-77-9

Chemical Formula: C8-H20-N-O6-P

Molecular Weight: 257

Mol. Mass:  257.22

Alpha GPC is a chemical released when a fatty acid found in soy and other plants breaks down. It is used as medicine, used in cosmetics, dietary supplyments and food, 

In Europe alpha-GPC is a prescription medication for the treatment of Alzheimer’s disease. It is available in two forms; one is taken by mouth, and the other is given as a shot. In the United States alpha-GPC is only available as a dietary supplement, mostly in products promoted to improve memory.

Other uses for alpha-GPC include treatment of various kinds of dementia, stroke, and “mini-stroke” (transient ischemic attack, TIA). Alpha-GPC is also used for improving memory, thinking skills, and learning.

How does it work?

Alpha GPC seems to increase a chemical in the brain called acetylcholine. This brain chemical is important for memory and learning functions.

Alpha GPC, also known as alpha-glycerylphosphorylcholine, is a nutrient now available as a supplement. It is able to deliver choline to the brain. Whether it offers advantages over choline, cdp-choline, acetyl l-carnitine which are also available as oral supplements, is not yet known for certain. Alpha GPC is not a phospholipid, rather it is a nutrient derived from soy phospholipids, one of these phospholipids being lecithin.

Alpha GPC, also known as choline alfoscerate is a phospholipid metabolite found concentrated in neuronal membranes. Made from lecithin, it is well absorbed and crosses the blood brain barrier. In the brain it supports brain function and learning processes by directly increasing the synthesis and secretion of acetylcholine. It protects neurons and improves signal transmission by serving as a precursor to membrane phospholipids.

Alpha GPC (L-alphaglycerophosphatidylcholine; also known as choline alfoscerate) is a phospholipid metabolite found concentrated in neuronal membranes. Derived from lecithin; Alpha GPC is extremely well absorbed and crosses the blood brain barrier. In the brain; Alpha GPC supports brain function and learning processes by directly increasing the synthesis and secretion of acetylcholine. Alpha GPC protects neurons and improves signal transmission by serving as a precursor to membrane phospholipids.

Alpha-GPC Possible Benefits:

Medline summary:

Alpha-GPC or GPC has been documented extensively by published studies in both animals and humans to contribute to at least five (5) significant human health functions.

These relevant 'mind-body' activities include, but may not be limited to the following:

1. Increases human Growth Hormone (hGH)

Increases in endogenous human Growth Hormone (hGH) secretion by the anterior pituitary in conjunction with Growth Hormone Releasing Hormone (GHRH); that is, both Alpha-GPC and GHRH act concertedly to stimulate the release of hGH, naturally;

2. Improved mental focus and stimulation of cognitive function

Stimulation of the enzymatic synthesis of phosphatidylcholine (PC) in nerves, muscle cells and all cell membranes, counteracting the age-related decrease in phospholipid (PC) biosynthesis; thus, Alpha-GPC contributes directly to improved mental focus and stimulation of cognitive function;

3. More strength from work-outs and training programs

Acts as a precursor of acetylcholine (ACh); thus, Alpha-GPC activates cholinergic transmission which permits the development of more strength from work-outs and training programs, plus reducing levels of somatostatin in the hypothalamic-pituitary axis;

4. Improved lipotrophic functions in the liver

Elevations in blood and tissue levels of the essential nutrient, choline, which supports improved lipotrophic functions (methyl group transferases) in the liver. Research has shown that fatty liver, a condition associated with obesity, diabetes and heavy alcohol consumption, often leads to cirrhosis of the liver or liver failure. Studies conducted by Alan L. Buchman, M.D., associate professor of medicine at The Feinberg School of Medicine at Northwestern University, have shown that fatty liver can be prevented and possibly even eliminated with increased levels of choline. Alpha-GPC also acts synergistically with the body's store (and/or supplementation) of S-adenosyl-L-methionine (SAM or SAMe) and folic acid, vitamin B12 and vitamin B6 to facilitate methyl group transfers in the brain and liver;

5. Improved balanced and coordination

Produces improved balanced and coordination when combined with 'skill set' practice and training as a result of normalized nerve transmission in the brain, and in cardiac, skeletal and smooth muscles.

More Alpha-GPC Information & Possible Benefits:

Alpha-GPC has been shown to potentiate the effects of growth hormone releasing hormone (GHRH) and increase human growth hormone (hGH) secretion in young and elderly individuals. Alpha-GPC also affects numerous biochemical and neurotransmitter systems that have been implicated in the development of age-related memory dysfunction (ARMD).

Administration of Alpha-GPC has been shown to improve neuropsychological parameters in patients with SDAT and ARMD. Alpha-GPC also improves memory and cognitive performance. Alpha-GPC has been shown to reduce the recovery time in comatose patients suffering from head injury and antagonize the effects of scopolamine to improve memory, attention, and performance in healthy individuals. Alpha-GPC's cognitive and growth hormone (GH) enhancing effects appear to be primarily the result of stimulation of the cholinergic neurotransmitter system; however, other biochemically-related modulations and neurotransmitter systems have been implicated.

Alpha-GPC improves memory, attention, and performance in healthy individuals. Alpha-GPC's cognitive and growth hormone (GH) enhancing effects appear to be primarily the result of stimulation of the cholinergic neurotransmitter system; however, other biochemically-related modulations and neurotransmitter systems have been implicated.

Contact us:

Mila Xue（薛慧）

Sales Director

Mobile: 0086 135 7299 1440 || Skype: live:mia_xuehui

Xi’an Rainbow Biotech Co., Ltd
---- Manufacturer of plant and herbal extract Rm:701, Building B, Haibo Plaza, Fengcheng No.9 Rd, Xi’an ETDZ, Shaanxi, China 0086-29-81319106 ext 805 || mila@rainbow-biotech.com || www.rainbowextract.com 

2% 4% 5% 98% nuciferine Lotus Leaf Extract by Rainbow Biotech

Product Name: Lotus Leaf Extract     

Latin Name: Folium Nelumbinis

Active Ingredient: Nuciferine 2% 4% 5% 10% 98%

Flavones 10%-40%

Ratio 10:1

Test Method:HPLC/ UV

Extraction Solvent:Ethanol/ Water

CAS NO.:475-83-2

Molecular Formula:C19H21NO2

Molecular Weight :313.39082

The lotus leaf (Nelumbo nucifera) is an aquatic perennial. This plant has white flowers with light green leaves and grows throughout the tropical regions of Asia and the Middle East. Known by many other names including the sacred lotus, Indian lotus, Chinese arrowroot, and Egyptian bean, it has an extensive history. In fact, the sacred lotus has been used as a medicinal herb for thousands of years.

 

The entire lotus plant has been used in Chinese medicine for treating everything from diarrhea to bleeding ulcers. Lotus leaves were also highly regarded as a weight-loss cure, as the plant is a diuretic. One of the main functions of the lotus leaf plant is to stop bleeding associated with excessive menstruation, hemorrhoids, and vomiting of blood. All parts of the plant can be used as an astringent and cardio tonic. In addition, lotus is employed as a treatment for mushroom poisoning.

 

Dried lotus leaf is available at many herbal shops. Additionally, the plant can be found in pill, powder, and capsule form. Lotus is considered safe and has no known negative side effects.

Rainbow Biotech is top manufacturer of Lotus Leaf Extract in China over decade years, we're ISO HALAL manufacturer 2% 4% 5% 10% 50% 98% nuciferine  wih best price, for more details pls contact us mila@rainbow-biotech.com

 Water Soluble Lotus Leaf Extract

Lotus Leaf Extract Nuciferine 2% 10% 98%

Lotus Leaf Extract Nuciferine 98% Crystal

Lotus Leaf Extract HPLC FINGERPRINT By Rainbow Biotech

What are the Benefits of Lotus Leaf Extract?

Lotus Leaf Extract Weight Loss

The lotus has historically played an important role in both the religion and medicine of many cultures. According to Plant Cultures, the lotus "has been held sacred in Asia and the Middle East for over 5,000 years." Texts from India dated to the 11th and 12th centuries discuss meals that feature lotus leaves. The resilient plant was considered a symbol of immortality for the ancient Egyptians who also made use of it in their diet.

The long history and varied claims have led to extensive research on the potential use of lotus leaf. According to a study in "Nutrition & Metabolism," lotus leaf extract, when combined with L-carnitine, "might represent a treatment option for obesity-related diseases." The mixture was shown to prevent adipogenesis, the formation of fatty tissue. Research conducted by Japanese scientists had similar results. The study monitored the effects of lotus leaf extract on obese mice for five weeks. The results showed that lotus leaf slowed the absorption of fat and carbohydrates, increased energy expenditure and accelerated lipid metabolism. Lotus leaf also prevented the increase of body weight.

Dosage of Lotus Leaf Extract

The appropriate dose of lotus depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for lotus. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Side effects of taking Lotus Leaf Extract

There is a lack of research regarding the effects of lotus leaf in pregnant women and it should be avoided. Lotus leaf may cause gastrointestinal irritation. Lotus leaf may increase the risk of bleeding and should not be used in conjunction with blood thinners, including aspirin. Consult your doctor before beginning treatment. 

Contact us:

Mila Xue ( Sales Manager)

Xian Rainbow Biotech Co.ltd

Tel： 0086-29-81319106

Skype: live:mia_xuehui

Mob: 0086 13572991440

POLICOSANOL: Introduction and Benefits

POLICOSANOL

OTHER NAME(S): 

32-C, Dotriacontanol, Heptacosanol, Hexacosanol, Nonacosanol, Octacosanol, Tetracosanol, Tétracosanol, Tetratriacontanol, Tétratriacontanol, Triacontanol 

Policosanol is a natural supplement made from sugar cane that is often used to lower cholesterol levels. It may also lower blood pressure and increase weight loss as well. However, there are conflicting studies that have questioned its benefits. Read on to discover the potential benefits and drawbacks of policosanol.

What is Policosanol?

Policosanol is a term for a group of long-chain alcohols extracted from the waxy coating of sugar cane. The first policosanol supplement was isolated and produced by researchers at Dalmer Laboratories in La Habana, Cuba, in the early 1990s.

It is commonly used for reducing high cholesterol, including total and LDL (low-density lipoprotein) cholesterol and has become one of the fastest growing over-the-counter supplements sold in the United States.

Most of the randomized trials that report positive benefits from policosanol were conducted by a single research group in Cuba and trials conducted by other groups have often failed to find any benefits .

Components of Policosanol

The components of policosanol are a mixture of high-molecular-weight aliphatic alcohols, with the main ones being

Octacosanol (60-70%)

Triacontanol (10-15%)

Hexacosanol (4.5-10%)

Dotriacontanol (3-8%)

Potential Benefits of Policosanol

1) Policosanol May Decrease LDL and Total Cholesterol

2) Policosanol May Increase HDL Cholesterol

3) Policosanol May Lower Triglyceride levels

4) Policosanol May Lower Blood Pressure

5) Policosanol May Help Reduce Blood Clots

6)Policosanol May Improve Symptoms of Intermittent Claudication

7) Policosanol May Improve Reaction Time

Contact us:

Mila Xue (Sales Manager

Mobile: 0086 135 7299 1440 || Skype: live:mia_xuehui

mila@rainbow-biotech.com

Xi’an Rainbow Biotech Co., Ltd
----Manufacturer of plant and herbal extract
Rm:701, Building B, Haibo Plaza, Fengcheng No.9 Rd, Xi’an ETDZ, Shaanxi, China
0086-29-81319106 ext 805 || mila@rainbow-biotech.com || www.rainbowextract.com 

Mobile: 0086 135 7299 1440 || Skype: live:mia_xuehui